![]() ![]() The simulated curves show the raw, non-normalized and unsmoothed data with a time-resolution of 2 ps. The data were generated in an overnight simulation including 60 million photons for each scattering law (total number of scattering events: 47 × 10 9). The curves in the inset of the bottom figure are polarization averaged. (170.3660) Light propagation in tissues (170.6935) Tissue characterization (290.1990) Diffusion (290.4210) Multiple scattering.Įxamples of the MC simulations where we varied the scattering law and its parameters. The interaction between the scattering particles and the gelatin matrix should be taken into account when developing such phantoms. The parameters determined at 780 nm are, ,, and The asymmetry parameter g obtained from the parameters and is 0.93, which indicates that the scattering entities are not bare TiO(2) particles but large sparse clusters. The excellent agreement between simulations and experiments confirmed the reliability of the results. The robustness of the method was verified with Monte Carlo simulations, where the experimentally obtained values served as input parameters for the simulations. For the determination of the key parameters μ(a) and, we employ a variant of time of flight measurements, where fiber optodes are immersed into the phantom to minimize the influence of boundaries. Here we employ a series of methods that aim to fully determine the optical properties, i.e., the refractive index n, absorption coefficient μ(a), transport mean free path, and scattering coefficient μ(s) of a TiO(2) in gelatin phantom intended for use in optoacoustic imaging. Tissue phantoms play a central role in validating biomedical imaging techniques. ![]()
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